Sanyu Babies Home was started as a venture of faith, love and hope in 1929 by a missionary sister, the late sister Milnes Walker. The mission was and continues to be one of receiving and caring for abandoned and parentless children.  Milnes Walker was working as a midwife at the nearby Church of Uganda Hospital where there were a number of babies being abandoned by their mothers shortly after delivery.  She began to take these babies in one by one and care for them at her home.  When it became evident that she could no longer care for so many children in this way, she obtained some land/house from the Church of Uganda and thus began Sanyu Babies Home.

The home is situated on Namirembe Hill overlooking Kampala City.  The home today continues to care for up to 40 abandoned and parentless babies and children of Uganda irrespective of race or creed, to bring them up in a happy, Christian atmosphere.

The children are aged from newborns to 5 years of age.  Often children are found in many varied places; from maternity wards, and hospitals; outside houses and, police stations; in taxis, and taxi parks; to rubbish dumps, pit latrines, and often just by the side of the road.

When a child is brought in efforts are made to find their parents or extended family but in most cases this proves unsuccessful.  The main objective of Sanyu Babies Home is to see the children resettled back into the community with relatives or with foster families. Some of the children at Sanyu are fostered and adopted into local and overseas families, the other children move onto other homes and orphanages as they get older.

The home today is run by Barbara Nankya Mutagubya.